Beschreibung
Research in the biomedical sciences is in crisis. Challenges to integrity resulting from fraud, plagiarism, misconduct, mishandling of research subjects and predatory publishing are everywhere. In order to meet its social mission the biomedical sciences are urgently in need of a unified concept of research integrity, defined as the trustworthiness of scientific quality and the ethical justifiability of research practices. Encompassing regulated areas -- subject protection, research misconduct and conflict of interest as well as newly quantified concerns about research bias and non-reproducibility, this book brings together the full range of practices and policies that should support research honestly produced and disseminated. It also specifically incorporates those topics noted by the NIH as essential and required for training in the responsible conduct of research (RCR). We have enclosed emails from two teachers of RCR attesting to the fact that there currently is no standard text or canon of readings that meet the demand that exists for teaching materials in this area. The Book The reader first frames the concept of research integrity and whether its performance is heading toward institutional corruption in the biomedical sciences. It then reviews evidence of the effectiveness of current governmental and self-regulation by the scientific community, from public participation and from meta-science studies, all of which are venues for intervention that will improve research integrity. The bulk of the Reader consists of the best classic publications and case examples in each of several areas: policy, methods, research subjects protection, conflicts of interest, research misconduct, plagiarism, reproducibility and whistleblowing as well as additional topics required for RCR instruction: mentor/mentee responsibilities and relationships, responsible authorship, peer review, and trustworthy data acquisition and management. Competition There is no other book that addresses this range of topics. Recent scholarship has illuminated the extent of unethical but unregulated practices that have wasted resources, misinformed the public, and caused harm. Previous books have examined a particular section of the regulated landscape: Cohen & Lynch (eds), Human subjects research regulation: perspectives on the future, MIT Press, 2014; and Barbara K. Redman's Research misconduct policy in biomedicine; beyond the bad apple approach, MIT Press, 2013. Most recently, the Interacademy Partnership has released Doing global science: A guide to responsible conduct in the global research enterprise, Princeton University Press, 2016. This slim volume reviews perspectives from national academies of science across the globe, reflecting their involvement in addressing issues of responsible conduct of research. Its emphasis is on the need for internationally harmonized standards, briefly enumerating research practices that should and should not be adopted. Discussion is very general whereas Getting to Good presents in-depth consideration of the full range of issues in research integrity and subject protection. Currently, courses, both the many required and elective in research integrity are using individual readings, frequently narrow in scope, often reflecting only the four NIH-required areas of instruction in responsible conduct of research. They neglect the broader set of issues and the overarching framework for research integrity because there is no single source that covers the entire spectrum of topic areas contained in this reader. At this time, there is a no competition for any comparable reader. Pressures for countries to meet international s
Autorenporträt
Arthur L Caplan, PhD Currently the Drs. William F and Virginia Connolly Mitty Professor and founding head of the Division of Bioethics at New York University Langone Medical Center in New York City. He is the head of the ethics program in the Global Institute for Public Health at NYU. Prior to coming to NYU he was the Sidney D. Caplan Professor of Bioethics at the University of Pennsylvania Perelman School of Medicine in Philadelphia where he created the Center for Bioethics and the Department of Medical Ethics. Caplan has also taught at the University of Minnesota, where he founded the Center for Biomedical Ethics, the University of Pittsburgh, and Columbia University. He received his PhD from Columbia University. Caplan is the author or editor of thirty-two books and over 600 papers in peer reviewed journals. His most recent book is Replacement Parts: The Ethics of Procuring and Replacing Organs in Humans (Georgetown University Press, 2015).He has served on a number of national and international committees including as the Chair, National Cancer Institute Biobanking Ethics Working Group; the Chair of the Advisory Committee to the United Nations on Human Cloning; the Chair of the Advisory Committee to the Department of Health and Human Services on Blood Safety and Availability; a member of the Presidential Advisory Committee on Gulf War Illnesses; the special advisory panel to the National Institutes of Mental Health on human experimentation on vulnerable subjects, the Wellcome Trust advisory panel on research in humanitarian crises, and the Co-Director of the Joint Council of Europe/United Nations Study on Trafficking in Organs and Body Parts. He is currently the ethics advisor to DOD/DARPA on synthetic biology, a member of the University of Pennsylvania's External Advisory Committee for its Orphan Disease Center and a member of the Ethics and Ebola Working Group of the World Health Organization. Dr. Caplan also serves as the Chairperson of the Compassionate Use Advisory Committee (CompAC), an independent group of internationally recognized medical experts, bioethicists and patient representatives which advises Janssen/J&J about requests for compassionate use of some of its investigational medicines. Caplan is the recipient of many awards and honors including the McGovern Medal of the American Medical Writers Association and the Franklin Award from the City of Philadelphia. He received the Patricia Price Browne Prize in Biomedical Ethics for 2011. He was a person of the Year-2001 from USA Today. He was described as one of the ten most influential people in science by Discover magazine in 2008. He has also been honored as one of the fifty most influential people in American health care by Modern Health Care magazine, one of the ten most influential people in America in biotechnology by the National Journal, one of the ten most influential people in the ethics of biotechnology by the editors of Nature Biotechnology and one of the 100 most influential people in biotechnology by Scientific American magazine. In 2014 he was selected to receive the Public Service Award from the National Science Foundation/National Science Board which honors individuals and groups that have made substantial contributions to increasing public understanding of science and engineering in the United States. He holds seven honorary degrees from colleges and medical schools. He is a fellow of the Hastings Center, the NY Academy of Medicine, the College of Physicians of Philadelphia, the American College of Legal Medicine and the American Association for the Advancement of Science. Barbara K. Redman, PhD, MBE is Associate, Division of Medical Ethics, New York Langone Medical Center. She is former Dean of the Wayne State University School of Nursing and over th
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