Beschreibung
Scientists may feel that there are too many meetings these days, and we tend to agree on this until it comes to our own field of interest. In our own areas we would like to hear about other people's achievements and learn whatever may be helpful in the search for answers to our own pet questions. Exchange of ideas, discussions, and critical evaluations are almost as essential to progress as the actual laboratory work. These were the major motives which initiated our own efforts, with the support of Dr. Earle H. Spaulding, the Chairman of the Department of Microbiology and Immunology at Temple University School of Medicine, to bring to gether for the first time specialists from various disciplines who are attempt ing to achieve the same thing, i. e., the clarification of the chemical and immunological nature of different cellular antigens. Instead of publishing the proceedings of the conference, it was decided that we would attempt to review achievements in the different subjects as well as report the latest developments from our own laboratories. Thus we hope to give scientists involved in this explosively growing field not only an up-to-date report, but also a useful source of relevant references. Despite these efforts and aspirations, we realize that this book is not a complete survey of all known cellular antigens. We tried to present major representations of the most important cell types.
Autorenporträt
Inhaltsangabe1 Gram-Negative Bacterial Antigens.- Immune Response of Mice to Subcellular Vaccines of Salmonella typhimurium.- The Common Antigen of Gram-Negative Enteric Bacteria.- Amino Sugars of Pseudomonas aeruginosa ATCC 7700 Lipopolysaccharide.- The Nature of Flagellar Antigens.- Summary Comments on Cellular Antigens of Gram-Negative Bacteria.- 2 Gram-Positive Bacterial Antigens.- Nature of the Streptococcal and Myocardial Antigens Involved in the Immunologic Cross-Reaction between Group A Streptococcus and Heart.- Polysaccharides of Hemolytic Streptococci.- Immunizing Antigens of Mycobacteria.- Gram-Positive Bacterial Antigens. Summary.- 3 Erythrocyte Antigens.- Isolation of the Blood Group A Receptor Component from Human Erythrocyte Membrane.- Antibody-, Virus- and Endotoxin-Receptors of Human Erythrocyte Membrane.- Effect of Periodate Oxidation and Borohydride Reduction on the Biology of the Major Glycoprotein of Human Erythrocytes.- Effect of Cetyltrimethylammonium Bromide on Human Erythrocyte Membranes.- Isolation of Erythrocyte Membrane Antigens. Summary.- 4 White Blood Cell Antigens.- Isolation and Properties of HL-A Antigens and Antigens of Neoplastic Mouse Plasma Cells.- Characterization and Isolation of HL-A Antigens from Continuous Cultured Human Lymphocyte Cell Lines: A Report of Current Progress.- Current Concepts of the HL-A System.- Interaction of Synthetic Antigens with the Unique Ribonucleoprotein of Macrophage Cells.- The Target (or Mode of Action) of Anti-Lymphocytic Antibodies.- Properties of Rabbit Antiserum to Mouse Thymocyte Membrane.- 5 Normal Tissue Antigens.- Membrane-Associated Histocompatibility Antigens.- Surface Antigens of Mammalian Cells.- The Subcellular Location of Antigens.- 6 Malignant Tissue Antigens.- Cellular Immunity to Tumor Antigens-Possible Clinical Usefulness of the Findings So Far Obtained.- Significance of the Cellular Antigens in Burkitt's Lymphoma.- Cross-Reactivity between SV40-Transformed Cell Surface Antigen and Early Embryo Antigen.- Role of Tumor Antigens in the Biology of Neoplasia.- Some Comments on the Role of Blocking Serum Factors in Tolerance to Allografts.- A Cytokinetic Factor in the Seromucoid Fraction of Serum or Ascites Fluid in Tumor-Bearing Hamsters.- Summary of the Tumor Antigens Session.- Author Index.
