Beschreibung
Inhaltsangabe1 Introduction.- 1.1 Review of the Mental Health Programme of the World Health Organization (WHO).- 1.2 Related Efforts of the Organization.- 1.3 Reasons for Undertaking a Study Using Benzodiazepines.- 1.4 Acknowledgement.- 2 Literature Review.- 2.1 Literature on Cross-Cultural Comparisons of Effectiveness of Psychotropic Drugs.- 2.2 Literature on Cross-Cultural Comparisons of Psychotherapy.- 2.3 Literature on Methodological Issues Involved in the Conduct of Comparative Studies.- 2.4 Literature About Administrative/Procedural Aspects of Multicentric Trials.- 3 Aims of the Study.- 4 Description of Materials and Methods.- 4.1 Design of the Study.- 4.2 Description of Centres at Which the Study Took Place.- 4.2.1 Description of Research Centre and Study Area of Bombay.- 4.2.2 Description of Research Centre and Study Area of Ibadan.- 4.2.3 Description of Research Centre and Study Area of London.- 4.2.4 Description of Research Centre and Study Area of Tokyo.- 4.3 Description of Samples and Manner of Selection.- 4.3.1 Description of Samples.- 4.3.2 Manner of Selection of Patients for the Study.- 4.4 Description of Instruments Used for Assessment and Training of Research Workers.- 4.4.1 General Health Questionnaire (GHQ).- 4.4.2 Present State Examination (PSE).- 4.4.3 Rating Scale for Side Effects (RSSE).- 4.4.4 General Practitioner's Rating-Need for Treatment Scale.- 4.4.5 Demographic Description.- 4.4.6 Brief Life Events Questionnaire (BLEQ).- 4.4.7 Personal Treatment Record.- 4.4.8 Audit of Counselling.- 4.5 Treatments.- 4.5.1 Choice of Drugs and Dosage.- 4.5.2 Counselling.- 5 Results.- 5.1 Assessment of the Value of Instruments Used.- 5.2 Overall Comparisons Among Centres.- 5.2.1 Comparison of GHQ Total Scores at the Start of the Trial.- 5.2.2 Comparison of GHQ Scores Between Weeks 0 and 2.- 5.2.3 Comparison of GHQ Scores Between Weeks 0 and 6.- 5.2.4 Comparison of GHQ Scores Between Weeks 6 and 12.- 5.3 Within-Centre Comparisons (Between Methods and Treatments).- 5.3.1 Comparisons on Total GHQ Scores Between Weeks 0, 2 and 6.- 5.3.2 Comparisons on Total GHQ Scores Between Weeks 6 and 12.- 5.4 GHQ Factor Scores, Weeks 0 to 2 to 6.- 5.4.1 GHQ Factor B (Anxiety and Insomnia).- 5.4.2 GHQ Factor C (Social Dysfunction).- 5.5 Comparison of Scores on Present State Examination.- 5.5.1 Comparison on PSE Total Scores Between Weeks 0 and 6.- 5.5.2 Comparison of PSE Syndromal Scores (Weeks 0 to 6).- 5.6 Treatment-Emergent Symptoms.- 5.7 Physical Measurements.- 5.8 Brief Life Events Questionnaire.- 5.9 General Summary: Effects of Drugs and Counselling.- 6 Results: Analysis of Counselling.- 6.1 Difference Among Centres in Amount of Counselling.- 6.1.1 Total Interview Time.- 6.1.2 Number of Sessions of Counselling.- 6.2 Differences Among Centres in Methods of Counselling.- 6.3 Problem Areas Considered at Interview.- 6.4 Final Audit of Counselling.- 6.4.1 Final Audit of Items.- 6.4.2 Overall Evaluation of Counselling.- 7 Discussion.- 7.1 Indirect Evaluation of Treatments.- 7.2 Evaluation of Treatments with Scales.- 7.2.1 Effects of Treatments to Week 6.- 7.2.2 Effects of Treatments to Weeks 6 to 12.- 7.3 General Improvement.- 7.4 Effects of the Study on Participating Centres.- 7.5 Methodological Limitations.- 7.6 Further Work.- 8 Conclusions.- References.- Appendix A: Description of Research Centres and Study Areas.- Appendix B: Data Collection Forms.
