Diagnosis of benign and malignant lesions of thyroid by FNAC and AgNO3

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Silver Nitrate stained Nucleolar Organizer Regions of DNA (AgNORs) by Fine Needle Aspiration Cytology (FNAC) smear

ISBN: 3659717142
ISBN 13: 9783659717147
Autor: Mohammed Abdul, Rasheed/Syed, Parween Mazher Ali/Mohammed, Amanullah
Verlag: LAP LAMBERT Academic Publishing
Umfang: 76 S.
Erscheinungsdatum: 06.06.2015
Auflage: 1/2015
Format: 0.5 x 22 x 15
Gewicht: 131 g
Produktform: Kartoniert
Einband: KT
Artikelnummer: 8268750 Kategorie:

Beschreibung

Benign thyroid nodules are common in adults and thyroid malignancy is the most common malignancy of endocrine system. Papillary thyroid carcinoma and follicular thyroid carcinoma are often curable and prognosis is good if identified in early stage.To avoid unnecessary surgery 'Fine needle aspiration cytology' (FNAC) is used as a diagnostic tool to differentiate benign nodule from malignant nodule. To improve the diagnostic accuracy of FNAC ,silver nitrate staining technique is applied. Smear from patients is stained with silver nitrate and nucleolar organising regions (segments of DNA) were stained as brown/black spots called AgNORs. Neoplastic and non-neoplastic lesions are differentiated by this technique. A total number of 119 cases were subjected to FNAC. Most cases occurred in females(94%) Maximum number of cases were seen in age group 21 to 30 years. There was significant higher AgNORs score in malignant lesions.

Autorenporträt

Dr. Mohammed Abdul Rasheed is M.B.B.S from Kakatiya Medical College, Warangal, India, M.D. Pathology from Dr. NTR University of health sciences, India. Presently working as Assistant professor in Department of Pathology, Shadan Institute of Medical sciences, Hyderabad, India. Worked as clinician in Saudi Arabia & India for more than two decades.

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