Produktbild: Targeted Protein Degradation

Targeted Protein Degradation

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235,39 €

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Methods and Protocols, Methods in Molecular Biology 2365

ISBN: 1071616641
ISBN 13: 9781071616642
Herausgeber: Angela M Cacace/Christopher M Hickey/Miklós Békés
Verlag: Springer Verlag GmbH
Umfang: xi, 351 S., 17 s/w Illustr., 50 farbige Illustr., 351 p. 67 illus., 50 illus. in color. With online files/update.
Erscheinungsdatum: 26.08.2021
Auflage: 1/2021
Produktform: Gebunden/Hardback
Einband: Gebunden

This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Targeted Protein Degradation: Methods and Protocols aims to ensure successful results in this emerging field of drug discovery.

Artikelnummer: 1592047 Kategorie:

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