Produktbild: Antimalarial Natural Products

Antimalarial Natural Products

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160,49 €

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Progress in the Chemistry of Organic Natural Products 117

ISBN: 3030898725
ISBN 13: 9783030898724
Herausgeber: A Douglas Kinghorn/Heinz Falk/Simon Gibbons et al
Verlag: Springer Verlag GmbH
Umfang: ix, 106 S., 104 s/w Illustr., 8 farbige Illustr., 106 p. 112 illus., 8 illus. in color.
Erscheinungsdatum: 04.01.2022
Auflage: 1/2022
Produktform: Gebunden/Hardback
Einband: Gebunden

This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine’s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine’s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature’s combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends by identifying ten natural products with development potential as clinical antimalarial agents.

Artikelnummer: 2895804 Kategorie:

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E-Mail: juergen.hartmann@springer.com

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