Vertebrate Eye Development

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53,49 

Results and Problems in Cell Differentiation 31

ISBN: 3642536786
ISBN 13: 9783642536786
Herausgeber: M Elizabeth Fini
Verlag: Springer Verlag GmbH
Umfang: xiv, 288 S., 72 s/w Illustr., 2 farbige Illustr., 288 p. 74 illus., 2 illus. in color.
Erscheinungsdatum: 31.08.2012
Auflage: 1/2012
Produktform: Kartoniert
Einband: Kartoniert

The power of molecular genetics has recently returned the discipline of Developmental Biology to its original position at the forefront of biological research. The vertebrate eye was one of the classic embryologic models in the early 1900s. Within the last decade of the 20th century, a return to some of the old questions with the new approaches has put eye development back into the limelight. This book provides an up-to-date and comprehensive overview of the field. The latest advances in delineating genetic hierarchies for eye development in animals are discussed, as well as their relationship to congenital disorders of the eye which affect humans. Since studies in Drosophila have provided significant insight, chapters on this invertebrate model are included. In addition, a number of related areas are discussed which are unique to this book: developmental anatomy of the eye from the perspective of its optical function, recent advances in understanding how the retina connects to the brain, the role of extracellular matrix and cell adhesion molecules in eye development, and two chapters on eye regeneration in amphibians and fish.

Artikelnummer: 6482373 Kategorie:

Beschreibung

"Who would believe that so small a space could contain the images of all the universe?" Leonardo da Vinci The last years of the 20th century have found the discipline of Developmental Biology returning to its original position at the forefront of biological re search. This progress can be attributed to the burgeoning knowledge base on molecules and gene families, and to the power of the molecular genetic ap proach. Topping the list of organ systems which have provided the most significant advances would have to be the eye. The vertebrate eye was one of the classic embryologic models, used to demonstrate many important prin ciples, including the concepts of inductive tissue interactions first put forth in the early 1900s. Within the last decade of this century, a return to some of the old questions with the new approaches has put eye development back into the limelight. I find this a highly appropriate topic for a book which aims to spark research for the new millennium. We begin with a chapter that discusses the anatomy of eye development, providing the basic reference information for the chapters that follow. A novel aspect of this introduction is the connection made between develop mental strategies and the eye's optical function. What also emerges from this chapter is the number of important eye structures that have barely been touched by the modern developmental biologist. Work on cornea and ante rior chamber development has lagged behind lens and retina.

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