Histone Deacetylases

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Methods and Protocols, Methods in Molecular Biology 1436

ISBN: 1493936654
ISBN 13: 9781493936656
Herausgeber: Sibaji Sarkar
Verlag: Humana Press
Umfang: xii, 337 S., 21 s/w Illustr., 31 farbige Illustr., 337 p. 52 illus., 31 illus. in color.
Erscheinungsdatum: 01.06.2016
Auflage: 1/2016
Produktform: Gebunden/Hardback
Einband: GEB

This volume provides different methodologies for all classes of histone deacetylases, which includes detailed procedures on Class I and II histone deacetylase inhibitors, SIRT inhibitors, and bromodomain inhibitors. Histone Deacetylases: Methods and Protocols is divided into four sections: Sections A and B describe methodologies used to detect the activity, function, or chromatin location of HDACs 1 through 11, with Section A discussing Class I and Section B discussing class II histone deacetylases; Section C focuses on the methodologies for cloning and characterizing the acetylation of SIRTs 1 through 7; and Section D describes methods related to histone deacetylase inhibitors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Histone Deacetylases: Methods and Protocols, is a valuable resource for investigators working on epigenetics, molecular biology, and genetics.

Artikelnummer: 9085743 Kategorie:

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