Mitochondrial DNA

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Methods and Protocols, Methods in Molecular Biology 2615

ISBN: 1071629212
ISBN 13: 9781071629215
Herausgeber: Thomas J Nicholls/Jay P Uhler/Maria Falkenberg
Verlag: Springer Verlag GmbH
Umfang: xv, 469 S., 17 s/w Illustr., 68 farbige Illustr., 469 p. 85 illus., 68 illus. in color. With online files/update.
Erscheinungsdatum: 21.02.2023
Auflage: 1/2023
Produktform: Gebunden/Hardback
Einband: GEB

This volume compiles a comprehensive range of methods to study key aspects of mitochondrial DNA including nucleoid structure and packaging, replication, genome integrity, and disease. Chapters are organized into eight methodological sections that cover in vitro and in vivo methods, including for mtDNA isolation, visualization, deep sequencing, gene editing, and diagnostic aspects of mtDNA disease. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Mitochondrial DNA: Methods and Protocols aims to be useful and informative for researchers and clinicians with an interest in mitochondrial DNA.

Artikelnummer: 6620924 Kategorie:

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