Produktbild: Solving a 3D Structural Puzzle

Solving a 3D Structural Puzzle

Lieferzeit: Lieferbar innerhalb 14 Tagen

106,99 €

inkl. 7 % MwSt. zzgl. Versandkosten

Springer Theses

ISBN: 3319961713
ISBN 13: 9783319961712
Autor: Hoeck, Casper Rønn
Verlag: Springer Verlag GmbH
Umfang: xli, 238 S., 93 s/w Illustr., 74 farbige Illustr., 238 p. 167 illus., 74 illus. in color.
Erscheinungsdatum: 13.11.2018
Auflage: 1/2018
Produktform: Gebunden/Hardback
Einband: Gebunden

This book explores how nuclear magnetic resonance (NMR) spectroscopy may be used for spatial structural elucidation of novel compounds from fungal and synthetic sources. Readers will discover the exciting world of NOE (nuclear Overhauser effect), RDC (residual dipolar coupling) and J-coupling constants, both short- and long range. With emphasis on obtaining structural knowledge from these NMR observables, focus is moved from solving a static 3D structure to solving the structural space inhabited by small organic molecules. The book outlines the development and implementation of two Heteronuclear Multiple Bond Correlation-type NMR experiments, and the 3D structural elucidation of multiple known and novel compounds. In addition, a new method of back-calculating RDCs (allowing for more flexible structures to be investigated), and the synthesis and evaluation of novel chiral alignment media for ab initio determination of absolute stereochemistry of small molecules using RDCs are also included. Challenges that 3D structural generation of small compounds face are also covered in this work.

Artikelnummer: 5246331 Kategorie:

Beschreibung

Herstellerkennzeichnung:


Springer Verlag GmbH
Tiergartenstr. 17
69121 Heidelberg
DE

E-Mail: juergen.hartmann@springer.com

Das könnte Ihnen auch gefallen …