A Master Regulator of Oxidative StressThe Transcription Factor Nrf2

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129,00 

ISBN: 953512837X
ISBN 13: 9789535128373
Herausgeber: Jose Antonio Morales-Gonzalez/Angel Morales-Gonzalez/Eduardo Osiris Madrigal-Santillan
Verlag: IntechOpen
Umfang: 210 S., 40 farbige Illustr.
Erscheinungsdatum: 21.12.2016
Auflage: 1/2016
Format: 1.9 x 26.6 x 18.5
Gewicht: 672 g
Produktform: Gebunden/Hardback
Einband: Gebunden
Artikelnummer: 7071871 Kategorie:

Beschreibung

Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways.

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