Molecular Genetics of Liver Neoplasia

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213,99 

Cancer Genetics

ISBN: 1461427312
ISBN 13: 9781461427315
Herausgeber: Xin Wei Wang/Joe W Grisham/Snorri S Thorgeirsson
Verlag: Springer Verlag GmbH
Umfang: xiv, 399 S., 16 s/w Illustr., 30 farbige Illustr.
Erscheinungsdatum: 25.12.2012
Auflage: 1/2014
Produktform: Kartoniert
Einband: KT

Cancer is a genetic disease and cancer research is a broad discipline embracing investigators and clinicians with diverse backgrounds. This new edition of Molecular Genetics of Liver Neoplasia intends to provide a comprehensive view on genetics and a mechanistic understanding of liver cancer. The book covers from molecular pathogenesis and cellular origin to translational genomics of liver cancer. The leading experts in the field of liver cancer have thoroughly summarized the latest developments and have provided current viewpoints and novel concepts. This cutting-edge volume is a vital resource for today’s basic cancer researchers, graduate students, medical students and clinicians interested in hepatocarcinogenesis.

Artikelnummer: 4249458 Kategorie:

Beschreibung

InhaltsangabePart I: Introduction 1. Overview of HCC: biology and pathology Xin Wei Wang, Joe Grisham and Snorri Thorgeirsson 2. Overview of CC: Part II: Liver development and pathogenesis 3. Embryonic development of the liver Kenneth S. Zaret 4. Human hepatic cell lineages Nelson Fausto 5. Pathology of Human Liver Cancer Masamichi Kojiro Part III: Genetics and epidemiology of liver cancer 6. HCC Hashem El.Serag 7. CC Greg Gores Part IV: Molecular Basis of Cancer Susceptibility 8. Yusuke Nakamura (NCC) 9. Hereditary liver diseases with a high risk to develop HCC Markus Grompe, [ALSO Marie-Annick Buendia] 10. Genetics and epigenetics of preneoplastic liver diaseses and human HCC 11. HBV: Jack Wands 12. HCV: Stanly Lemon 13. Fibrosis and cirrhosis studies David Brenner 14. Methylation status in chronic liver disease and HCC Yae Kanai (Japan) Part V. Animal models 15. Transgenic mouse models Snorri Thorgeirsson & Joe Grisham 16. Mosaic mouse model Scott Lowe 17. Zebrafish model Zhiyuan Gong (NUS): Part VI: Global gene expression profiling of human liver cancer 18. Integrative and functional genomics of HCC Snorri Thorgeirsson: 19. Molecular signatures of metastatic HCC Xin Wei Wang 20. Liver cancer heterogeneity and tumor subtypes Jessica Rossi 21. Gene expression studies in cholangiocarcinoma Yoichi Furokawa Part VII: Cancer stem cells 22. Snorri Thorgeirsson 23. Tania Roskams Part VIII: Liver cancer genetics in the clinic 24. Biomarkers and clinical staging of liver cancer Josep Llovet 25. Molecular signaling in HCC Hong Yang Wang (Shanghai) 26. Molecular oncology and HCC ZhaoYou Tang (Shanghai) 27. Molecular pathogenesis of HCC Irene Ig (Hong Kong)

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