Beschreibung
The present book describes a one-pot, TBA-HS catalyzed method for the synthesis of benzopyran-fused pyranopyrazoles via a domino Knoevenagel hetero Diels-Alder (DKHDA) reaction of some olefin-ether-tethered aldehyde substrates with pyrazolones as an active methylene unit. The aldehyde substrates were obtained by allylating or prenylating 5-aryldiazenylaldehydes. The stereochemistry of all the compounds was confirmed by various 2D NMR experiments; DQF-COSY and NOESY, and single crystal X-Ray diffraction analysis. The entire synthesized compound also screened for their antimicrobial, antituberculosis and antioxidant properties. It is hoped that post-graduate and Ph.D. students will find this book more useful in their research work.
Autorenporträt
Dr. Shashikant B. Teraiya, Post doct Fellow, Prof. Hai-Liang Zhu Group,State Key Laboratory of Pharmaceutical Biotechnology, School of life sciences,Nanjing University,Nanjing 210093, PR China,
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