Beschreibung
InhaltsangabePREFACE ix CONTRIBUTORS xi 1 LYSOPHOSPHATIDIC ACID (LPA) RECEPTOR SIGNALING 1 Hope Mirendil, Mu-En Lin, and Jerold Chun 2 SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTORS 41 Bongnam Jung and Timothy Hla 3 GLOBAL GENE EXPRESSION PROGRAM OF LYSOPHOSPHATIDIC ACID (LPA)-STIMULATED FIBROBLASTS 61 Catelijne Stortelers and Wouter H. Moolenaar 4 IDENTIFICATION OF DIRECT INTRACELLULAR TARGETS OF SPHINGOSINE 1-PHOSPHATE (S1P) 71 Nitai C. Hait, Sheldon Milstien, and Sarah Spiegel 5 LYSOPHOSPHOLIPID RECEPTOR SIGNALING PLATFORMS: THE RECEPTOR TYROSINE KINASE-G PROTEIN-COUPLED RECEPTOR SIGNALING COMPLEX 85 Nigel J. Pyne and Susan Pyne 6 AUTOTAXIN: A UNIQUE ECTO-TYPE PYROPHOSPHODIESTERASE WITH DIVERSE FUNCTIONS 103 Hiroshi Yukiura and Junken Aoki 7 STUDIES ON AUTOTAXIN SIGNALING IN ENDOCYTIC VESICLE BIOGENESIS AND EMBRYONIC DEVELOPMENT USING WHOLE EMBRYO CULTURE AND ELECTROPORATION 121 Masayuki Masu, Seiichi Koike, Takuya Okada, and Kazuko Keino-Masu 8 STANDARDIZATION AND QUANTIFICATION OF LYSOPHOSPHATIDIC ACID COMPOUNDS BY NORMAL-PHASE AND REVERSED-PHASE CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY 137 Jeff D. Moore, Shengrong Li, David S. Myers, Stephen B. Milne, H. Alex Brown, and Walter A. Shaw 9 SPHINGOSINE KINASES: BIOCHEMISTRY, REGULATION, AND ROLES 153 Melissa R. Pitman, Kate E. Jarman, Tamara M. Leclercq, Duyen H. Pham, and Stuart M. Pitson 10 FUNCTIONAL AND PHYSIOLOGICAL ROLES OF SPHINGOSINE 1-PHOSPHATE TRANSPORTERS 185 Atsuo Kawahara and Tsuyoshi Nishi 11 LIPID PHOSPHATE PHOSPHATASES AND SIGNALING BY LYSOPHOSPHOLIPID RECEPTORS 201 Ganesh Venkatraman and David N. Brindley 12 LIPID PHOSPHATE PHOSPHATASES: RECENT PROGRESS AND ASSAY METHODS 229 Andrew J. Morris, Susan S. Smyth, Abdel K. Salous, and Andrew D. Renault 13 LYSOPHOSPHATIDIC ACID (LPA) SIGNALING AND CARDIOVASCULAR PATHOLOGY 265 Susan S. Smyth, Anping Dong, Jessica Wheeler, Manikandan Panchatcharam, and Andrew J. Morris 14 SPHINGOSINE 1-PHOSPHATE (S1P) SIGNALING IN CARDIOVASCULAR PHYSIOLOGY AND DISEASE 283 Bodo Levkau 15 SPHINGOSINE 1-PHOSPHATE (S1P) SIGNALING AND THE VASCULATURE 313 Christian Waeber 16 REGULATION OF THE NUCLEAR HORMONE RECEPTOR PPARgamma BY ENDOGENOUS LYSOPHOSPHATIDIC ACIDS (LPAS) 349 Ryoko Tsukahara, Tamotsu Tsukahara, and Gabor Tigyi 17 MECHANISMS AND MODELS FOR ELUCIDATING THE CARDIAC EFFECTS OF SPHINGOSINE 1-PHOSPHATE (S1P) 373 Shigeki Miyamoto, Sunny Yang Xiang, Nicole H. Purcell, and Joan Heller Brown 18 NEURAL EFFECTS OF LYSOPHOSPHATIDIC ACID (LPA) SIGNALING 399 Nobuyuki Fukushima 19 WIDESPREAD EXPRESSION OF SPHINGOSINE KINASES AND SPHINGOSINE 1-PHOSPHATE (S1P) LYASE SUGGESTS DIVERSE FUNCTIONS IN THE VERTEBRATE NERVOUS SYSTEM 419 H. Meng and V.M. Lee 20 LYSOPHOSPHATIDIC ACID AND NEUROPATHIC PAIN: DEMYELINATION AND LPA BIOSYNTHESIS 433 Hiroshi Ueda 21 ROLE OF LYSOPHOSPHATIDIC ACID (LPA) IN BEHAVIORAL PROCESSES: IMPLICATIONS FOR PSYCHIATRIC DISORDERS 451 Guillermo Estivill-Torrús, Luis Javier Santín, Carmen Pedraza, Estela Castilla-Ortega, and Fernando Rodríguez de Fonseca 22 SPHINGOSINE 1-PHOSPHATE (S1P) SIGNALING AND LYMPHOCYTE EGRESS 475 Alejandra Mendoza, Lauren A. Pitt, and Susan R. Schwab 23 BIOLOGY REVEALED BY SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR GENE-ALTERED MICE 489 Maria L. Allende, Mari Kono, Aikaterini Alexaki, Christina Giannouli, Jiman Kang, Catherine C. Theisen, Eleanor L. Koerner, and Richard L. Proia 24 ROLE OF LYSOPHOSPHATIDIC ACID (LPA) IN THE INTESTINE 507 C. Chris Yun and Peijian He 25 LYSOPHOSPHOLIPID SIGNALING IN FEMALE AND MALE REPRODUCTIVE SYSTEMS 529 Xiaoqin Ye 26 THE GONADS AND THEIR MAGIC BULLET, LYSOPHOSPHATIDIC ACID: PHYSIOLOGICAL AND TOXICOLOGICAL FUNCTIONS OF LYSOPHOSPHATIDIC ACID (LPA) IN FEMALE AND MALE REPRODUCTIVE SYSTEMS 569 Lygia Therese Budnik, Bärbel Brunswig-Spickenheier, and Dieter Müller 27 LYSOPHOSPHOLIPID REGULATION OF LUNG FIBROSIS 587 Barry S. Shea and Andrew M. Tager 28 LYSOPHOSPHATIDIC ACID (LPA) SIGNALI
Autorenporträt
InhaltsangabePREFACE ix CONTRIBUTORS xi 1 LYSOPHOSPHATIDIC ACID (LPA) RECEPTOR SIGNALING 1 Hope Mirendil, Mu-En Lin, and Jerold Chun 2 SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTORS 41 Bongnam Jung and Timothy Hla 3 GLOBAL GENE EXPRESSION PROGRAM OF LYSOPHOSPHATIDIC ACID (LPA)-STIMULATED FIBROBLASTS 61 Catelijne Stortelers and Wouter H. Moolenaar 4 IDENTIFICATION OF DIRECT INTRACELLULAR TARGETS OF SPHINGOSINE 1-PHOSPHATE (S1P) 71 Nitai C. Hait, Sheldon Milstien, and Sarah Spiegel 5 LYSOPHOSPHOLIPID RECEPTOR SIGNALING PLATFORMS: THE RECEPTOR TYROSINE KINASE-G PROTEIN-COUPLED RECEPTOR SIGNALING COMPLEX 85 Nigel J. Pyne and Susan Pyne 6 AUTOTAXIN: A UNIQUE ECTO-TYPE PYROPHOSPHODIESTERASE WITH DIVERSE FUNCTIONS 103 Hiroshi Yukiura and Junken Aoki 7 STUDIES ON AUTOTAXIN SIGNALING IN ENDOCYTIC VESICLE BIOGENESIS AND EMBRYONIC DEVELOPMENT USING WHOLE EMBRYO CULTURE AND ELECTROPORATION 121 Masayuki Masu, Seiichi Koike, Takuya Okada, and Kazuko Keino-Masu 8 STANDARDIZATION AND QUANTIFICATION OF LYSOPHOSPHATIDIC ACID COMPOUNDS BY NORMAL-PHASE AND REVERSED-PHASE CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY 137 Jeff D. Moore, Shengrong Li, David S. Myers, Stephen B. Milne, H. Alex Brown, and Walter A. Shaw 9 SPHINGOSINE KINASES: BIOCHEMISTRY, REGULATION, AND ROLES 153 Melissa R. Pitman, Kate E. Jarman, Tamara M. Leclercq, Duyen H. Pham, and Stuart M. Pitson 10 FUNCTIONAL AND PHYSIOLOGICAL ROLES OF SPHINGOSINE 1-PHOSPHATE TRANSPORTERS 185 Atsuo Kawahara and Tsuyoshi Nishi 11 LIPID PHOSPHATE PHOSPHATASES AND SIGNALING BY LYSOPHOSPHOLIPID RECEPTORS 201 Ganesh Venkatraman and David N. Brindley 12 LIPID PHOSPHATE PHOSPHATASES: RECENT PROGRESS AND ASSAY METHODS 229 Andrew J. Morris, Susan S. Smyth, Abdel K. Salous, and Andrew D. Renault 13 LYSOPHOSPHATIDIC ACID (LPA) SIGNALING AND CARDIOVASCULAR PATHOLOGY 265 Susan S. Smyth, Anping Dong, Jessica Wheeler, Manikandan Panchatcharam, and Andrew J. Morris 14 SPHINGOSINE 1-PHOSPHATE (S1P) SIGNALING IN CARDIOVASCULAR PHYSIOLOGY AND DISEASE 283 Bodo Levkau 15 SPHINGOSINE 1-PHOSPHATE (S1P) SIGNALING AND THE VASCULATURE 313 Christian Waeber 16 REGULATION OF THE NUCLEAR HORMONE RECEPTOR PPARgamma BY ENDOGENOUS LYSOPHOSPHATIDIC ACIDS (LPAS) 349 Ryoko Tsukahara, Tamotsu Tsukahara, and Gabor Tigyi 17 MECHANISMS AND MODELS FOR ELUCIDATING THE CARDIAC EFFECTS OF SPHINGOSINE 1-PHOSPHATE (S1P) 373 Shigeki Miyamoto, Sunny Yang Xiang, Nicole H. Purcell, and Joan Heller Brown 18 NEURAL EFFECTS OF LYSOPHOSPHATIDIC ACID (LPA) SIGNALING 399 Nobuyuki Fukushima 19 WIDESPREAD EXPRESSION OF SPHINGOSINE KINASES AND SPHINGOSINE 1-PHOSPHATE (S1P) LYASE SUGGESTS DIVERSE FUNCTIONS IN THE VERTEBRATE NERVOUS SYSTEM 419 H. Meng and V.M. Lee 20 LYSOPHOSPHATIDIC ACID AND NEUROPATHIC PAIN: DEMYELINATION AND LPA BIOSYNTHESIS 433 Hiroshi Ueda 21 ROLE OF LYSOPHOSPHATIDIC ACID (LPA) IN BEHAVIORAL PROCESSES: IMPLICATIONS FOR PSYCHIATRIC DISORDERS 451 Guillermo Estivill-Torrús, Luis Javier Santín, Carmen Pedraza, Estela Castilla-Ortega, and Fernando Rodríguez de Fonseca 22 SPHINGOSINE 1-PHOSPHATE (S1P) SIGNALING AND LYMPHOCYTE EGRESS 475 Alejandra Mendoza, Lauren A. Pitt, and Susan R. Schwab 23 BIOLOGY REVEALED BY SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR GENE-ALTERED MICE 489 Maria L. Allende, Mari Kono, Aikaterini Alexaki, Christina Giannouli, Jiman Kang, Catherine C. Theisen, Eleanor L. Koerner, and Richard L. Proia 24 ROLE OF LYSOPHOSPHATIDIC ACID (LPA) IN THE INTESTINE 507 C. Chris Yun and Peijian He 25 LYSOPHOSPHOLIPID SIGNALING IN FEMALE AND MALE REPRODUCTIVE SYSTEMS 529 Xiaoqin Ye 26 THE GONADS AND THEIR MAGIC BULLET, LYSOPHOSPHATIDIC ACID: PHYSIOLOGICAL AND TOXICOLOGICAL FUNCTIONS OF LYSOPHOSPHATIDIC ACID (LPA) IN FEMALE AND MALE REPRODUCTIVE SYSTEMS 569 Lygia Therese Budnik, Bärbel Brunswig-Spickenheier, and Dieter Müller 27 LYSOPHOSPHOLIPID REGULATION OF LUNG FIBROSIS 587 Barry S. Shea and Andrew M. Tager 28 LYSOPHOSPHATIDIC ACID (LPA) SIGNALI
