Beschreibung
InhaltsangabeContributors. Preface. The Siren's Song: This Death That Makes Life Live (Gerry Melino, Richard A Knight and Jean-Claude Ameisen). The Origin and Evolution of Programmed Cell Death (Jean Claude Ameisen). Cell Death in C. elegans (Ataman Sendoel and Michael O Hengartner). Caspases and Cell Death (Lorraine D Hernandez, Caroline Houde, Maarten Hoek, Brent Butts, Donald W Nicholson and Huseyin Mehmet). The Apoptosome: The Executioner of Mitochondria-mediated Apoptosis (Elisabetta Ferraro and Francesco Cecconi). Caspases, Substrates and Sequential Activation (John G Walsh and Seamus J Martin). Dismantling the Apoptotic Cell (Paula Deming and Sally Kornbluth). The BCL2 Family Proteins Key Regulators and Effectors of Apoptosis (David L Vaux). BH3only Proteins (Lina Happo, Andreas Strasser and Clare L Scott). Mitochondrial Outer Membrane Permeabilization (Melissa J Parsons and Douglas R Green). Mitochondria Fusion and Fission (Giovanni Benard, Guihong Peng and Mariusz Karbowski). Death Receptors (Peter H Krammer and Inna N Lavrik). Death Receptors at the Molecular Level: Therapeutic Implications (Marion MacFarlane). Death Receptor-induced Necroptosis (Wim Declercq, Franky Van Herreweghe, Tom Vanden Berghe and Peter Vandenabeele). Inhibitor of Apoptosis (IAP) and BIR-containing Proteins (David L Vaux). Structures, Domains and Functions in Cell Death (DD, DED, CARD, PYD) (Hao Wu and Yu-Chih Lo). Structure and Function of IAP and Bcl-2 Proteins (Mark G Hinds, Peter D Mace and Catherine L Day). Engulfment of Apoptotic Cells and its Physiological Roles (Rikinari Hanayama, Masanori Miyanishi, Hiroshi Yamaguchi, Jun Suzuki and Shigekazu Nagata). Autophagy (María Isabel Colombo and Hans-Uwe Simon). Autophagy in Nonmammalian Systems (Jahda H Hill and Eric H Baehrecke). Apoptosis: Regulatory Genes and Disease (James E Vince and John Silke). Caspases in Inflammation and Immunity (Philippe M LeBlanc and Maya Saleh). Immunity, Granzymes and Cell Killing (Nigel J Waterhouse, Olivia Susanto, Karin A Sedelies and Joseph A Trapani). P53 and Cell Death (Kamil Wolyniec, Sue Haupt and Ygal Haupt). Cornification of the Skin: A Non-apoptotic Cell Death Mechanism (E Candi, RA Knight and G Melino). Apoptosis: Inherited Disorders (Helen C Su and Michael J Lenardo). From Reactive Oxygen and Nitrogen Species to Therapy (Scott R McKercher, Tomohiro Nakamura and Stuart A Lipton). Microbial Inhibitors of Apoptosis (Georg Häcker). Drug Discovery in Apoptosis (Tom O'Brien and Vishva M Dixit). Subject Index.
Inhaltsverzeichnis
Contributors. Preface. The Siren''s Song: This Death That Makes Life Live (Gerry Melino, Richard A Knight and Jean-Claude Ameisen). The Origin and Evolution of Programmed Cell Death (Jean Claude Ameisen). Cell Death in C. elegans (Ataman Sendoel and Michael O Hengartner). Caspases and Cell Death (Lorraine D Hernandez, Caroline Houde, Maarten Hoek, Brent Butts, Donald W Nicholson and Huseyin Mehmet). The Apoptosome: The Executioner of Mitochondria-mediated Apoptosis (Elisabetta Ferraro and Francesco Cecconi). Caspases, Substrates and Sequential Activation (John G Walsh and Seamus J Martin). Dismantling the Apoptotic Cell (Paula Deming and Sally Kornbluth). The BCL-2 Family Proteins - Key Regulators and Effectors of Apoptosis (David L Vaux). BH3-only Proteins (Lina Happo, Andreas Strasser and Clare L Scott). Mitochondrial Outer Membrane Permeabilization (Melissa J Parsons and Douglas R Green). Mitochondria Fusion and Fission (Giovanni Benard, Guihong Peng and Mariusz Karbowski). Death Receptors (Peter H Krammer and Inna N Lavrik). Death Receptors at the Molecular Level: Therapeutic Implications (Marion MacFarlane). Death Receptor-induced Necroptosis (Wim Declercq, Franky Van Herreweghe, Tom Vanden Berghe and Peter Vandenabeele). Inhibitor of Apoptosis (IAP) and BIR-containing Proteins (David L Vaux). Structures, Domains and Functions in Cell Death (DD, DED, CARD, PYD) (Hao Wu and Yu-Chih Lo). Structure and Function of IAP and Bcl-2 Proteins (Mark G Hinds, Peter D Mace and Catherine L Day). Engulfment of Apoptotic Cells and its Physiological Roles (Rikinari Hanayama, Masanori Miyanishi, Hiroshi Yamaguchi, Jun Suzuki and Shigekazu Nagata). Autophagy (MarÃa Isabel Colombo and Hans-Uwe Simon). Autophagy in Nonmammalian Systems (Jahda H Hill and Eric H Baehrecke). Apoptosis: Regulatory Genes and Disease (James E Vince and John Silke). Caspases in Inflammation and Immunity (Philippe M LeBlanc and Maya Saleh). Immunity, Granzymes and Cell Killing (Nigel J Waterhouse, Olivia Susanto, Karin A Sedelies and Joseph A Trapani). P53 and Cell Death (Kamil Wolyniec, Sue Haupt and Ygal Haupt). Cornification of the Skin: A Non-apoptotic Cell Death Mechanism (E Candi, RA Knight and G Melino). Apoptosis: Inherited Disorders (Helen C Su and Michael J Lenardo). From Reactive Oxygen and Nitrogen Species to Therapy (Scott R McKercher, Tomohiro Nakamura and Stuart A Lipton). Microbial Inhibitors of Apoptosis (Georg Häcker). Drug Discovery in Apoptosis (Tom O''Brien and Vishva M Dixit). Subject Index.
